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Development of a real-time full-field OCT for 3D tomography on biological tissue : Date:

University of Kassel – Prof. Dr.-Ing Peter Lehmann

Optical coherence tomography (OCT) is a method for the 3D examination of biological tissue samples. © Adobe Stock / Angelov

Recipient: University of Kassel
Funding: GO-Bio initial conceptual phase 4 (01/10/2023 to 30/09/2024, EUR 120,000.00)

Project description: 

Optical coherence tomography (OCT) is a method for the 3D examination of biological tissue samples. It offers unique opportunities to obtain information from inside a sample without the need for special preparation. Most commercial OCT systems today are based on point-by-point scanning of the sample. These systems must consequently screen over the sample to obtain 2D or 3D tomograms. One way to capture tomograms is full-field OCT (FFOCT). At present, however, FFOCT is slower than the previously mentioned method of point-type sampling. However, the FFOCT is superior to the previously mentioned sensors in terms of resolution and flexibility, among other things. The starting point of the present project idea is a novel image acquisition and evaluation concept for a flat OCT sensor that can record several tomograms per second and evaluate them in real time. The experimental set-up is intended to implement the novel image acquisition and evaluation concept in such a way that high-resolution OCT images can be achieved with several 3D tomograms per second at a short measurement time. In the upcoming exploratory phase a concept for the best possible utilisation of the OCT method is to be developed. For this purpose an IP strategy is to be developed, the market is to be analysed, the team is to be enlarged and initial preliminary investigations are to be carried out.